Super-secondary structures involving triple-strand β-sheets

Secondary structures involving the poly(A) tail and other

In Saccharomyces cerevisiae, previous measurements of mRNA stabilities have been determined on a per-gene basis. We and others have recently shown that yeast genes give rise to a highly heterogeneous population of mRNAs thanks to extensive alternative 3' end formation. Typical genes can have fifty or more distinct mRNA isoforms with 3' endpoints differing by as little as one and as many as hund...

Conformational analysis and design of cross-strand disulfides in antiparallel β-sheets.

Cross-strand disulfides bridge two cysteines in a registered pair of antiparallel β-strands. A nonredundant data set comprising 5025 polypeptides containing 2311 disulfides was used to study cross-strand disulfides. Seventy-six cross-strand disulfides were found of which 75 and 1 occurred at non-hydrogen-bonded (NHB) and hydrogen-bonded (HB) registered pairs, respectively. Conformational analys...

Subordination and Super Ordination Results Involving Certain Convolution Operators

Secondary instability of salt sheets

In the presence of a vertically varying horizontal current (background shear), the salt-fingering instability is supplanted by the salt-sheet instability. Previous direct numerical simulation (DNS) experiments on salt sheets revealed that flow becomes turbulent via secondary instabilities. We call these instabilities zig-zag and tip modes. Here, we investigate the physics of these modes using l...

Conformational modulation of peptide secondary structures using β-aminobenzenesulfonic acid.

This communication describes the influence of β-aminobenzenesulfonic acid ((S)Ant) on the conformational preferences of hetero foldamers. The designed (Aib-(S)Ant-Aib)n and (Aib-(S)Ant-Pro)n oligomers display a well-defined folded conformation featuring intramolecular mixed hydrogen bonding (7/11) and intra-residual (6/5) H-bonding interactions, respectively.